DIAGNOSTIC VALUE OF ANTI-PEPTIDYLARGININE DEIMINASE TYPE 4 (PADI-4) AND ANTI- CITRULLINATED PEPTIDE ANTIBODIES (ACCP) IN IRAQI PATIENTS WITH RHEUMATOID ARTHRITIS
نویسندگان
چکیده
منابع مشابه
diagnostic value of anti-cyclic citrullinated peptide antibodies in patients with rheumatoid arthritis
objective: anti-cyclic citrullinated peptide (anti-ccp) antibodies are highly specific markers for rheumatoid arthritis (ra) and useful for predicting rheumatoid arthritis (ra) development and progression. we assessed the diagnostic value of anti-ccp antibodies in our patients with ra. materials and methods: anti-ccp antibodies and rheumatoid factor (rf) titers were determined in 247 serum sam...
متن کاملThe diagnostic value of anti-cyclic citrullinated peptide antibodies in patients with rheumatoid arthritis.
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. The aim of this study was to evaluate the diagnostic value of anti CCP antibodies in patients with RA. This study included three groups; group I: 60 early diagnosed RA patients selected according to the ACR, group II: 30 patients of arthritis other than RA, group III: 10 healthy age and sex matche...
متن کاملDiagnostic value of anti-cyclic citrullinated peptide antibodies in Greek patients with rheumatoid arthritis
BACKGROUND Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been of diagnostic value in Northern European Caucasian patients with rheumatoid arthritis (RA). In these populations, anti-CCP antibodies are associated with the HLA-DRB1 shared epitope. We assessed the diagnostic value of anti-CCP antibodies in Greek patients with RA where the HLA shared epitope was reported in a minority...
متن کامل[Diagnostic and prognostic value of antibodies to cyclic citrullinated peptide (Anti-CCP) in rheumatoid arthritis].
There is strong evidence that the determination of autoantibodies against filaggrine is a very useful tool for the diagnosis of rheumatoid arthritis (RA). Anti-cyclic citrullinated peptide antibodies (Anti-CCP)-ELISA appear to be the most efficient test among those available for the detection of antifilaggrine autoantibodies, as it has the best diagnostic accuracy for the diagnosis of RA. Furth...
متن کاملLocalization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis.
OBJECTIVES Peptidylarginine deiminases (PADIs) convert peptidylarginine into citrulline via post-translational modification. Anti-citrullinated peptide antibodies are highly specific for rheumatoid arthritis (RA). Our genome-wide case-control study of single-nucleotide polymorphisms found that the PADI4 gene polymorphism is closely associated with RA. Here, we localized the expression of PADI4 ...
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ژورنال
عنوان ژورنال: Basrah Journal of Surgery
سال: 2014
ISSN: 2409-501X
DOI: 10.33762/bsurg.2014.91009